A series of examination and procedures are required to assess overall health of the patient and to prepare the patient physically for transplant surgery after it is decided that disease of the patient can be treated with bone marrow transplant. These tests, which investigate if the recipient and donor meet certain criteria, may take several days to complete.
A catheter is inserted into one of the major veins inside the patient’s body shortly before the transplant stage.Bone marrow can be suctioned out of the bone with a special needle in autologous transplantation cases.
Another method is to administer a medication to the patient which increases the stem cell production in the bone marrow and ensures that the stem cells are released into blood. Next, stem cells inside the patient’s blood circulation are harvested with a procedure, called apheresis.
Next, stem cells or bone marrow are frozen and stored to be used after treatment of the main disease. The first step of allogeneic bone marrow transplant is to find an appropriate donor for the patient. The stem cells obtained from peripheral blood or bone marrow of the donor are frozen and stored until the transplant surgery is performed.
For both transplant groups, the cancer, condition which damages the bone marrow, is treated with high-dose medications before the bone marrow transplantation. Next, immune system of the patient is suppressed and the frozen blood cells are transferred to the patient via catheter. Stem cells migrate to the bone marrow of the patient following bone marrow transplant and divide there.
Next, production of healthy blood cells begins. The immune system is suppressed for a period of time determined by the physician. Moreover, risks of infection, bleeding and anemia caused by low blood values are supervised and treated.
The bone marrow starts functioning properly and the blood cell counts are restored to normal ranges within a few weeks under normal circumstances, but it may also take longer in case of any complication. Patients are transfused red blood cells or platelets to manage the conditions caused by low blood counts in this period.
Otherwise, infections or other complications may prolong the hospital stay and cause negative effects on the success of the transplant.The transplant patients are informed in detail regarding precautions they are required to take for their lives after the transplant before they are discharged. Moreover, it is critical for the patients to use medications that are prescribed during discharge strictly as instructed by the physician.
Organ transplantation success rates in global hospital and physician network of Hera Healthcare are comparable to or above the global averages. Transplant patients are closely monitored and have the option to contact us at the minute they have any concern after being discharged.
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